Electron Microscope Image Through the Whole Retina
Eyewire is so named because we are mapping neurons of the retina. The image above shows a labeled cross-section through the whole retina, from photoreceptors to ganglion cells. It may be surprising to see just how tall the photoreceptors are — the largest being at least twice as tall as the tallest ganglion cell. The image above was generated by Seung Lab’s Sebastian Stroeh using an electron microscope. The image below from Zeiss highlights different retinal cells.
The current Eyewire dataset focuses on the Inner Plexiform Layer. We reconstructed the ganglion cells during the Countdown to Neuropia (2014-25) and are currently reconstructing the cells of the Inner Nuclear Layer in The Dig. You can check out all the cells mapped in Eyewire at museum.eyewire.org.