About EyeWire, A Game to Map the Brain

Sourcefed EyewireEyeWire is a game to map the brain from Seung Lab at MIT. Anyone can play and you need no scientific background. Over 130,000 people from 145 countries already do. Together we are mapping the 3D structure of neurons; advancing our quest to understand ourselves.

 

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By joining EyeWire, you can help map the connectome, starting with connections between retinal neurons. EyeWire gameplay advances neuroscience by helping researchers discover how neurons connect and network to process information. You also help the EyeWire team, based at MIT, develop advanced artificial intelligence and computational technologies for mapping the connectome.

How it Works

In EyeWire, players are challenged to map branches of a neuron from one side of a cube to the other.  Think of it as a 3D puzzle. Players scroll through the cube (measuring about 4.5 microns per side or ~10x smaller than the average width of a human hair) and reconstruct neurons in volumetric segments with the help of an artificial intelligence algorithm developed at Seung Lab.

For fun. For science!for science, eyewire, neuroscience, science design, design, eyewire design, brain design

EyeWire holds regular competitions and a weekly “happy hour” on Friday from 2 to 4 pm EST. During challenges, players compete for bonuses, profile icons, unique chat colors and even neuron naming rights. In-game trivia occasionally takes place through chat. Players level up in EyeWire by beating the Starburst Challenge, unlocking the right to map difficult starburst neurons and earn double points. Advanced players participate in Hunts, where they scour completed cells looking for mergers or mistake branches that need to be scythed away by an ominous, in-game overlord character known as the GrimReaper. If a player finds enough, she is promoted to Scout and eventually many attain EyeWire’s highest ranking, Order of the Scythe.

EyeWire at TEDxAmsterdam:

Watch Sebastian Seung’s TEDTalk

In The News

Hundreds of articles have been written about EyeWire since it launched in Dec 2012. Find a list of prominent publications here

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Credits

Founder and Principal Investigator: Sebastian Seung

Full Stack Developers: William Silversmith, Katya Radul

Back End Developers: Matt Balkam, Shang Mu

Algorithms, AI and data structures: Aleks Zlateski, Kisuk Lee

edX Fellowship: Claire O’Connell

Neuroimaging: Ashwin Vishwanathan

Design: Alex Norton and Beth Almeida

Neuroscience: Jinseop Kim

Game Masters: Rachel Prentki, Lyndsey Trawinski, Marissa Sorek, Aleksandra Ostojic, Celia David, Ross Avery, Sean Temple

Creative Director: Amy Robinson

MIT UROPs: Aaron Hammond, Dmetri Hayes Michael Purcaro, David Jia, Brett Warne and Rachel Shearer participated in early work on software development. Daniel Berger has assisted with 3D renderings. EyeWire is based on images of the retina acquired at the Max Planck Institute of Medical Research in Heidelberg, Germany by Kevin Briggman, Moritz Helmstaedter, and Winfried Denk using a method known as serial block-face scanning electron microscopy.

EyeWire is currently funded by the National Institutes of Health, and was originally made possible by support from the Gatsby Charitable Foundation, the Howard Hughes Medical Institute, and the Max Planck Society. Former team members: Mark Richardson, Leandro Burnes, Srini Turaga, Matt Susskind Special Thanks: Elizabeth Bailey, Rachel Cuozzo, Alan Diaz-Romero, Emilio Gonzalez, Jonathan Gootenberg, Shaunak Kishore, Yinqing Li, Greg Lubin, Tomer Mangoubi, Claire O’Connell, Ami Patel, Laya Rajan, Christopher Smith, Jacob Steinhardt, Jessica Sun, Arvind Thiagarajan, and Jason Toy All EyeWire images, screenshots and animations are licensed Creative Commons-Share Alike, non-commercial. We kindly request that you contact support at eyewire dot org before publishing any of our images.

 

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