About Eyewire, A Game to Map the Brain

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Eyewire is a game to map the brain in collaboration with the Seung Lab at Princeton. Anyone can play and you need no scientific background — over 200,000 people from 145 countries already do. Together we are mapping the 3D structure of neurons; advancing our quest to understand ourselves.


play eyewire a game to map the brain


By joining Eyewire, you can help map the connectome, starting with connections between retinal neurons. Eyewire gameplay advances neuroscience by helping researchers discover how neurons connect and network to process information. You also help develop advanced artificial intelligence and computational technologies for mapping the connectome.


How it Works

In Eyewire, players are challenged to map branches of a neuron from one side of a cube to the other.  Think of it as a 3D puzzle. Players scroll through the cube (measuring about 4.5 microns per side or ~10x smaller than the average width of a human hair) and reconstruct neurons in volumetric segments with the help of an artificial intelligence algorithm developed at Seung Lab.

For fun. For science!for science, eyewire, neuroscience, science design, design, eyewire design, brain design

As you trace through each neuron you’ll rack up points based on speed, skill and accuracy.  Trace your way to the top of the leaderboard, engage in themed competitions against your Eyewire friends, and earn badges to show off your Eyewire achievements.  If you’re good enough you can climb the ranks to Advanced Player, Scout, and the prestigious Order of the Scythe.

Look out for special in-game competitions as well.  Eyewire holds a weekly Friday “Happy Hour” (2-4 PM EST), bi-weekly VS competitions, and bi-monthly themed competitions full of mini games that offer competitors limited edition badges, loads of points bonuses, and even Eyewire themed swag.

Eyewire is also a great way to meet friends from across the globe.  Some of our players have even met up in person.  Check out these Featured Eyewirers to learn a little more about the members of our favorite online community!

Eyewire 101

Sebastian Seung’s TEDTalk

In The News


Hundreds of articles have been written about EyeWire since it launched in Dec 2012. Find a list of prominent publications here

EyeWire ONFIRE, neuron, branches


Eyewire Team

Founder and Principal Investigator: Sebastian Seung

Executive Director: Amy R. Sterling

Full Stack Developers: William Silversmith, Chris Jordan

Back End Developers: Shang Mu

Development Interns: Alec Jordan

Algorithms, AI and data structures: Aleks Zlateski, Kisuk Lee

Neuroimaging: Ashwin Vishwanathan

Design: Alex Norton

Neuroscience: Jinseop Kim

Gamemasters: Rachel Prentki, Marissa Sorek, Celia David, Doug Bland, Devon Jones

Tracers: Merlin Moore, Kyle Willie, Ben Silverman


Former Team Members:

MIT UROPs: Aaron Hammond, Dmetri Hayes Michael Purcaro, David Jia, Brett Warne and Rachel Shearer participated in early work on software development. Claire O’Connell (edX fellowship).

Development team: Mark Richardson, Leandro Burnes, Srini Turaga, Matt Susskind, Katya Radul, Matt Balkam, Anna Lee

Tracers: Lindsey Trawinski, Alex Ostojic, Ross Avery, Sean Temple, Mike Weiss, Ian Danskin, Joanna Wheatley

Design Interns: Beth Almeida, Luke Hollyer, Amy Concannon, Chengcheng Xiao, Nicole Benson, Montakan Namthong

Daniel Berger has assisted with 3D renderings. EyeWire is based on images of the retina acquired at the Max Planck Institute of Medical Research in Heidelberg, Germany by Kevin Briggman, Moritz Helmstaedter, and Winfried Denk using a method known as serial block-face scanning electron microscopy.

eyewire title GIF

Eyewire is currently funded by Korea Telecom, the National Institutes of Health, the Gatsby Charitable Foundation, and the Intelligence Advanced Research Projects Activity (IARPA). It was originally made possible by support from the Gatsby Charitable Foundation, the Howard Hughes Medical Institute, and the Max Planck Society.

Special Thanks: Elizabeth Bailey, Rachel Cuozzo, Alan Diaz-Romero, Emilio Gonzalez, Jonathan Gootenberg, Shaunak Kishore, Yinqing Li, Greg Lubin, Tomer Mangoubi, Claire O’Connell, Ami Patel, Laya Rajan, Christopher Smith, Jacob Steinhardt, Jessica Sun, Arvind Thiagarajan, and Jason Toy.

All Eyewire images, screenshots and animations are licensed Creative Commons-Share Alike, non-commercial. We kindly request that you contact support at eyewire dot org before publishing any of our images.

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